Abstracts
Feodor Lynen Lecture:
Lipid packing defects: a journey with a fuzzy but insightful concept in molecular membrane biology
Bruno Antonny
Institute of Molecular and Cellular Pharmacology, 660, route des Lucioles, Sophia Antipolis, 6560 Valbonne, France, antonny@ipmc.cnrs.fr
In this plenary presentation, I will evoke key milestones of the work of my team and of other colleagues over the past twenty years. The recognition of imperfections in the packing of membrane lipids has been the common thread of this research. Such recognition by specific protein motifs enables the spatiotemporal organisation of numerous reactions at the surface of cellular organelles.