74th Mosbacher Kolloquium
"Immune Engineering - from Molecules to Therapeutic Approaches"

March 23 - 25, 2023


Dear Friends and Colleagues,

The traditional spring meetings of the German Society for Biochemistry and Molecular Biology (GBM) are held annually in the picturesque town of Mosbach to promote the exchange of scientific ideas, discuss emerging themes and to foster the education of young scientists.

The scientific theme of the 74th meeting is „Immune Engineering – from Molecules to Therapeutic Approaches“.
Harnessing the power of our immune system is currently emerging as the most promising avenue for previously uncurable diseases. Antibodies remain the mainstay of immune therapy and still hold major opportunities for the future. Engineering immune cell communication by tailor-made cytokines or directly editing the cells of our immune system as living drugs are exciting current developments in the field.


The Mosbacher Kolloquium in 2023 will bring together academic and industrial leaders in these fields. This will allow to obtain an overview over the state-of-the-art but also chart future developments in basic science and clinical translation.

We will provide a platform for fruitful scientific exchange of ideas that helps inspiring young scientists in their future research endeavors in this rapidly developing field.
We wish all of you a wonderful conference, lively exchange and fruitful contacts.

Matthias Feige
Dorothee Ambrosius
Christian Klein
Dirk Busch


Wednesday, March 22

16:00 - 19:45
Arrival and registration

18:00 - 19:30
Introductory lecture („Primer“)

Current topics in immune engineering
(delivered by the organizers)

Welcome reception

by the Lord Mayor of Mosbach and the president of GBM
(City hall of Mosbach)


Thursday, March 23

Opening remarks

09:00 - 12:00
Session 1:
Next generation antibody-based immunotherapies (Novel concepts: The scientific basis)

(Chairs: Dorothee Ambrosius & Christian Klein)

09:00 - 09:30
David Ho /New York [USA]
Title to be announced

09:30 - 09:45
Early career investigator talk 1
(to be selected from the abstracts)

09:45 - 10:15
Harald Kolmar /Darmstadt [DE]
Progress in antibody engineering (preliminary)

10:15 - 10:45
Coffee break
10:45 - 11:15
Mark Cragg /Southampton [UK]
Engineering antibodies for immune stimulation

11:15 - 11:30
Early career investigator talk 2
(to be selected from the abstracts)

11:30 - 12:00
Justin Taylor /Seattle [USA]
Exploiting B cells in human therapy (preliminary)

12:00 - 13:00
Lunch break

12:00 - 13:15
Meet the prof

(organized by the Junior GBM)

13:00 - 14:30
Poster session 1

(even poster numbers)

14:30 - 16:45
Session 1 (continued):
Next generation antibody-based immunotherapies (Novel concepts: Application in the clinic)

(Chairs: Dorothee Ambrosius & Christian Klein)

14:30 - 15:00
Pablo Umana /Zurich [CH]
Engineering antibodies for cancer immunotherapy (preliminary)

15:00 - 15:30
Dario Neri /Zurich [CH]
Novel developments on immunocytokines

15:30 - 16:00
Coffee break
16:00 - 16:30
Susanne Hipp /Biberach [DE]
T cell engagers: From research to clinic (preliminary)

16:30 - 16:45
Early career investigator talk 3
(to be selected from the abstracts)

16:45 - 17:00
Bayer Pharmaceuticals PhD Prize

(for applications see the announcement on the GBM webpage)

17:00 - 17:15
Karl Lohmann PhD Prize

(for applications see the announcement on the GBM webpage)

17:15 - 19:30
GBM General Meeting

(for GBM members only!)

19:30 - 20:30
Feodor Lynen Lecture

Erika Pearce /Baltimore [USA]
Delineating Cell Intrinsic Metabolic Pathways That Regulate T Cell Function

20:30 - 21:45
Poster session 2

(all poster numbers)

22:00 - 24:00
Get Together & Networking

(organized by the Junior GBM)


Friday, March 24

09:00 - 12:00
Session 2:
Engineering cytokines and their receptors

(Chair: Matthias Feige)

09:00 - 09:30
Rob Kastelein /Menlo Park [USA]
Title to be announced

09:30 - 09:45
Early career investigator talk 4
(to be selected from the abstracts)

09:45 - 10:15
Jürgen Scheller /Düsseldorf [DE]
Cytokine receptors in health and disease (preliminary)

10:15 - 10:45
Coffee break
10:45 - 11:15
Sebastian Kobold /Munich [DE]
Exploiting chemokine receptors in cancer therapy (preliminary)

11:15 - 11:30
Early career investigator talk 5
(to be selected from the abstracts)

11:30- 12:00
Title to be announced

12:00 - 13:00
Lunch break

12:00 - 13:15
Meet the prof

(organized by the Junior GBM)

14:30 - 16:00
Session 3:
Cell and virus-based therapeutical developments (Experiences and recent developments with CAR-T cells in the clinic)

(Chair: Dirk Busch)

14:30 - 15:00
Carl June /Philadelphia [USA]
CAR-T cells for therapy (preliminary)

15:00 - 15:30
Stan Riddell /Seattle [USA]
Novel developments in T cell engineering (preliminary)
15:30 - 16:00
Marion Subkleve /Munich [DE]
Title to be announced

16:00 - 16:30
Coffee break

17:30 - 18:30
Otto Warburg Medal

sponsored by:

Matthias Mann /Martinsried [DE]
Title to be announced


Saturday, March 25

09:00 - 10:30
Mini Symposium on Protein Engineering

(Chairs: Stefan Zielonka & Birte Höcker)

09:00 - 09:10
Introduction of the GBM Study Group "Protein Engineering & Design"

09:10 - 09:35
Jeanette Leusen /Utrecht [NL]
Engineering IgA for cancer therapy with neutrophils
09:35 - 10:00
2x Short talk
(to be selected from the abstracts)

10:00 - 10:30
Coffee break

10:30 - 12:15
Session 3:
Cell and virus-based therapeutical developments (Advanced lymphocyte and virus engineering technologies)

(Chair: Dirk Busch)

10:30 - 11:00
Chiara Bonini /Milan [IT]
Recent developments in genetic engineering of T cells (preliminary)

11:00 - 11:30
Yvonne Chen /Los Angeles [USA]
Exploiting synthetic biology in cell engineering (preliminary)
11:30 - 11:45
Early career investigator talk 6
(to be selected from the abstracts)

11:45- 12:15
Andreas Plückthun /Zurich [CH]
Rational engineering of proteins and viruses (preliminary)

12:15 - 13:15
Junior GBM Session

(Chair: N.N.)

12:15 - 12:45
Gregor Fuhrmann /Erlangen [DE]
Antibiotic resistance - challenge and new therapeutic perspectives
12:45 - 13:15
Sylvia Knapp /Wien [AT]
Title to be announced

13:15 - 13:30
Poster prizes & closing remarks




Early registration: January 31
Standard registration: March 8
Late registration: March 25

Abstract submission: January 31

Registration & Abstract Submission

Sponsoring & Industrial Exhibition

If you wish to present your company at the 74th Mosbacher Kolloquium of the GBM please see the pricelist for sponsoring and the exhibition or contact

Dr. Anke Lischeid
GBM Managing Director

Phone: +49 69 660567-12

Registration Fees

The registration fee includes coffee/tea/mineral water during the conference breaks.

Please note the general terms and conditions for payment and cancellation and our privacy policy.

If you want to join the GBM with your registration to enjoy the reduced participation fee, please fill in the online membership application (or fill the pdf application and send it to the GBM head office.

* member of the GBM, DECHEMA, DGZ, GDCh, VAAM, Bunsen Society
(Please bring a proof of your membership to the Kolloquium.) 

Registration fees for non-members*
Non-members* before
Feb 1
Mar 8
from Industry
330 390 420
PhD student 150 185 200
Master student
80 100 110
Retiree 80 100 110

All priceses in EURO

Registration fees for members*
Members* before
Feb 1
Mar 8
from Industry
300 360 390
PhD student 140 175 190
Master student
70 90 100
Retiree 70 90 100

All priceses in EURO

We thank for the kind support by:

Main Sponsor:




We do not have an overview of the current vacancies of the hotels in and around Mosbach. We therefore recommend booking via online portals such as booking.com or hotel.de.

The city of Mosbach publishes a list of hosts at https://www.mosbach.de


Please submit your abstract online after you finished the registration process. 
All neccessary information will be provide during the abstract submission process.
In case you are preparing your abstract offline please mind the maximum length of 1500 characters.

Conference Proceedings

Your name badge and a program booklet will be available at the registration desk. Please wear your name badge during the whole meeting.

We do not provide a abstract book. Please download the abstract pdf shortly before the meeting or use the online list of abstracts in the program booklet

Covid 19

We will apply the Corona rules of the state of Baden-Württemberg in effect at the time of the meeting.


As a young member of the GBM you can  apply for a travel grant (at the latest two months before the meeting).

Still not a member of the GBM? Here you can apply for it.

Internet & Email

A wireless LAN connection is available within the foyer of the Alte Maelzerei.

Meals & Drinks

Coffee, tea and mineral water will be provided for free during the coffee breaks.

Lunch is available at your own expense in the conference center or at the restaurants nearby in the town of Mosbach.


Numbers of the conference office (during the opening hours):

Tel. +49 6261 9292-78
Opening hours: 

Wednesday 16:00 - 19:45
Thursday 08:00 - 17.:00
Friday 08:30 - 16:00
Saturday 08.30 - 11.00


The poster should be presented in portrait format (DIN A0 resp. ~120 x 85 cm). Posters should be presented throughout the whole meeting. The best three posters will be awarded at the end of the meeting with a price money of 300 € each.


Alte Mälzerei
Alte Bergsteige 7
74821 Mosbach


As a participant from abroad you may need a visa from the German embassy. If so please contact the meeting secretariat. We will send you the required invitation letter.

Organization & Contact



Meeting Secretariat:

Gesellschaft für Biochemie
und Molekularbiologie


Mörfelder Landstr. 125
60598 Frankfurt am Main

+49 69 660567-0

Matthias Feige
Technical University of Munich [DE]

Dorothee Ambrosius
Boehringer-Ingelheim /Biberach [DE]

Dirk Busch
Technical University of Munich [DE]

Christian Klein
Roche Innovation Center /Zurich [CH]